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Research shows local cold application produces measurable reductions in inflammatory markers similar to whole-body approaches for localized injuries

SIMONETTO, MD Portal hypertensive bleeding encompasses a spectrum of conditions that include esophageal, gastric, and ectopic varices and portal hypertensive gastroenteropathy

It also modulates inflammatory signaling, reducing excessive inflammation that can impair healing while maintaining the beneficial inflammatory signals needed to recruit stem cells and initiate repair