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GH is secreted from somatotrophs in the anterior pituitary gland and is influenced positively by growth hormone-releasing hormone (GHRH) and inhibited by somatostatin

Among the experimentally characterized natively unfolded proteins included in that study (Uversky et al., 2000a), there were 7 proteins (7.8%), whose disordered status was confirmed by limited proteolysis, indicating the important role of this technique in establishing the IDP field