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However, long-term human safety data from controlled clinical trials is limited

Agmatine and sleep While Agm has been studied in the context of sleep-adjacent phenomena, such as enhanced anti-convulsant effects when Agm is co-delivered with the sleep-promoting indolamine melatonin (Moezi et al., 2011), I was unable to locate studies of Agm in the context of sleep per se , let alone its potential roles as a co-transmitter in this context

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