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During remodeling, osteoclasts resorb the irregular woven bone of the hard callus while osteoblasts deposit organized lamellar bone in its place

4.4.4 Orchestrating ICD via metal-organic frameworks (MOFs) The folate-modified MOF NP TPL@TFBF demonstrated precision induction of ferroptosis and pyroptosistwo ICD modalities

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Because cysteine is a rate-limiting substrate for glutathione synthesis, we hypothesized that 2-AB reflects glutathione compensation against oxidative stress