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In exploratory studies utilizing mice with HCA2 gene knockout (HCA2-KO), the severity of the inflammatory response to IMQ was found to be elevated, implicating a probable dysfunction in Treg cells ( In patients afflicted with psoriasis, an imbalance in gut microbiota has been observed

The participating cities also show different levels of preparedness to activate and engage with their local ecosystem during the Twinning Learning Programme, which is crucial for ensuring learning and knowledge transfer on institutional and societal levels and creating organisational memory