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In this connection, the toxic profile of tobacco mainstream smoke was characterized in different studies (114, 115), which makes it possible to investigate the impact of some of these chemicals on the complement system, using curated databases such as the comparative toxicogenomic database (CTD) to delineate possible impacted pathways (116)

In addition, most participants reported having a university-level education (73.8%), 46.2% reported having a monthly income of less than 5000 Saudi Arabian Riyal (SAR), and 20% described themselves as unemployed