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Pathogen exposure may trigger trained immunity in sarcoidosis, peripheral blood mononuclear cells (PBMCs) from patients produce higher TNF and IL-6 levels upon bacterial or fungal stimulation than those from healthy controls and show abnormal expression of pathogen-sensing PRRs (44)

Nanospheres, with diameters ranging from 101000 nm, consist entirely of polymer materials with drugs encapsulated or adsorbed within them

The slides were mounted with Fluoprep (BioMerieux), and immunofluorescence was viewed and analyzed using an Imager Z1 fluorescence microscope equipped with a Digital Camera (Zeiss, Jena, Germany) connected to an AxioVs40 software (Zeiss), and with an LMS800 confocal microscope piloted by a ZEN 2.3 software (Zeiss)

J., Dale, B