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Melatonins potential to strengthen the BBB appears to involve the upregulation of tight junction proteins, including claudin-5, zonula occludens-1, and occluding [191], which help shield the brain from harmful substances in the bloodstream [192]

Latina V, Caioli S, Zona C, Ciotti MT, Amadoro G, Calissano P

10.1016/j.biopha.2021.112115 52 YangF.TongJ.LiH.ChenJ.DaiL

Wiehle, Oral Enclomiphene Citrate Stimulates the Endogenous Production of Testosterone and Sperm Counts in Men with Low Testosterone: Comparison with Testosterone Gel, The Journal of Sexual Medicine, Volume 10, Issue 6, June 2013, Pages 16281635, 17