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Ongoing research is necessary to establish optimal administration strategies and comparative efficacy
Alternative TB-500 protocols for different goals Daily low-dose protocol For patients who prefer more frequent, lower-volume injections: Dose: 750 mcg 1 mg daily , subcutaneous Duration: 12 weeks continuous, then 4 weeks off Provides steady-state tissue levels without peaks and troughs of twice-weekly dosing Preferred by some patients with needle anxiety (smaller volume per injection) Body-weight-based TB-500 dosing Some practitioners calculate by weight for greater precision: Loading: 3060 mcg/kg per injection , twice weekly Maintenance: 30 mcg/kg once weekly For a 75 kg patient: loading = 2.254.5 mg per injection
Inflammatory Bowel Disease (IBD) : IBD is another common cause of vitamin B12 deficiency in dogs
Neurological deficit was assessed using the NIHSS on admission and after 24 h and 3-month mRS (with good outcome defined as 03)
