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Under FDA guidance documents and Chemical Safety Board recommendations, research-use-only (RUO) designation applies to chemical reagents, biological specimens, and investigational compounds sold exclusively for in vitro studies, animal research models, or mechanistic investigations conducted under controlled laboratory conditions

136, no

The disorder of acylcarnitine metabolism is related to the stage of liver disease, and with the deterioration of the disease, the disorder of acylcarnitine metabolism becomes more obvious [208]

Parallel in vitro experiments were performed using peritoneal macrophages harvested from a separate set of eight-week-old male Wistar rats weighing approximately 250 g